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Wine deal: Alois Lageder Müller Thurgau

I loves me some Müller-Thurgau, despite its legacy of being the prime ingredient in all those Liebfraumilch confections back in the day. One of the very best is the Alois Lageder Müller Thurgau ($18), a juicy, minerally mouthful of freshness.

NW sparklers start to shine

Wine columnist Paul Gregutt says that in the past couple of years not one but two boutique wineries have debuted in Washington committed to making méthode champenoise (traditional method) bubbly in both standard and not-so-standard styles.

Immunoproteasome crystal structure determined

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells that due to a viral infection present non-self peptides at their surface. In autoimmune diseases this mechanism is deregulated and the immune system also eliminates ...

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Elsevier Ltd is not responsible for the content of external websites. Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface.

Biochemists determine first crystal structure of an immunoproteasome

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells that due to a viral infection present non-self peptides at their surface. In autoimmune diseases this mechanism is deregulated and the immune system also eliminates ...